Influence of Plant Maturity on the Characteristics of Orange-Derived Extracellular Vesicles and Their Delivery Performance for Polyphenols AuthorHang Liu, Chen Yang, Xiaolin Wu, Shengfeng Peng,Lei Zhou, David Julian McClements, Wei Liu Year2025 Sourcehttps://papers.ssrn.com/sol3/papers.cfm?abstract_id=5164715 LanguageEnglish Pages1-43 3122Stability of extracellular vesiclesPhysical stabilityThe sedimentation potential of the colloidal particles in the orange juice samples was measured by subjecting them to a controlled centrifugal force using a stability analyzer (LUMiFuge 17 more LF). The instability index was then calculated to determine the physical stability of different samplesLUMiSizerLSMaturityOrange juiceextracellular vesiclePolyphenolsdelivery performancePlant-derived extracellular vesicles have considerable potential as natural pharmaceutical and nutraceutical delivery systems. Howeverthe impact of plant maturity on the physicochemical and structural properties of isolated extracellular vesicles is currently unknown. In this workextracellular vesicles isolated from oranges at different maturity stages were first characterized and compared. Afterwardspolyphenol-fortified orange juices were successfully prepared by incorporating polyphenols into extracellular vesicles originated from orange juices. Encapsulation in vesicles was found to increase the solubilitystabilitybioaccessibilityand antioxidant activity of curcuminbut the effects depended on the maturity of oranges. Specificallythe vesicles from unripe and ripe orange juices were more effective for curcumin delivery than those from overripe orange juice. More details Internal reference3122 Open publication →
Intensified co-precipitation and ion exchange using an agitated tubular reactor (ATR) for enhanced removal of Cs+ and Sr2+ ions AuthorOguzhan Kivan, Muhammad Yusuf, Rachael Filson-Halliwell, Jennifer N. Enemmoh, David Harbottle, Timothy N. Hunter Year2025 SourceChemical Engineering and Processing - Process Intensification LanguageEnglish Pages110077 3033LRXLUMiReader X-RayClinoptilolite 8 more Ion exchangeCoagulationAgitated tubular reactorProcess intensificationPressure filtrationComposite coagulants were synthesised in both a batch system and an agitated tubular reactor (ATR) using natural clinoptilolite with barite (BaSO4) co-precipitation for the intensified simultaneous removal of Cs+ and Sr2+ ions.The settling rates of composite flocs under the Earth’s gravitational force were analysed utilising a LUMiReader® X-Ray (L.U.M. GmbH) to understand to what degree the flocs create the fast settling beds without an external mechanical forceproviding insight into sludge consolidation. More details Edition207 Internal reference3033 Open publication →
Investigation of fuel cell catalyst dispersion formulations for indirect roll-to-roll fabrication of catalyst coated membranes for proton exchange membrane fuel cells AuthorL. Grebener, A.S. Odungat, Y. Zhu, O. Pasdag, I. Radev, E. Nürenberg, A. Kubina, V. Peinecke, S. Kohsakowski, D. Segets, F. Özcan Year2025 SourceJournal of Power Sources LanguageEnglish Pages236457 3047LFracLUMiFracProton exchange membrane fuel cell Catalyst coated membrane Roll-to-roll manufacturing Scalable technology 17 more he viability of the indirect process route for the fabrication of catalyst coated membranes for hydrogen fuel cells is demonstratedSpecimen assembly and adhesion measurement principle. After hot-pressing at 4.73 MPa the cut decal foil/CL/membrane tri-layer system is mounted in between a backplate and copper test mass. All together it is inserted in the guiding sleeve and the detector. On the centrifugal plateforces defined by the increasing rotation frequency are applied until the specimen breaks. The bi-layer specimens of the CL on decal foil are prepared likewiseby pressing the adhesive tape directly onto the CLCatalyst layer characterizationFor testing transferabilitythe centrifugal adhesion analyzer LUMiFracLUMiSizerLSinvestigate the dispersion behavioranalytical centrifugationACparticle size analysispsdpsaenergy storagetransition More details Edition635 Internal reference3047 Open publication →
INVITED REVIEW: Recent developments in understanding the rehydration characteristics of high-protein dairy powders AuthorS. Roy and J. K. Amamcharla Year2025 SourceJ. Dairy Sci. TBC LanguageEnglish Pages1-18 3020LUMiSizerLSfood 11 more nutritiondairy-based ingredients is increasingly prominent in the food industry due to their functional and nutritional benefits. High-protein powders are highly attractive due to their superior nutritional (e.g.high proteincalcium) and functional benefits (e.g.gelationemulsificationfoaming). solubilitycasein-rich ingredientsrehydration measurementDispersibilitysedimentation More details EditionAvailable online 6 January 2025 In Press, Journal Pre-proof Internal reference3020 Open publication →
Iron oxide nanoparticles: Surface chemistry and electrostatic stability influence silanization AuthorZeeshan Ali, Andrea Åvik Larsen, Sirsha Bandyopadhyay, Ahmad Bin Ashar, Sulalit Bandyopadhyay Year2025 SourceColloids and Surfaces A: Physicochemical and Engineering Aspects LanguageEnglish Pages136123 3118LSLUMiSizerIron oxide nanoparticles 9 more Silica coated iron oxide nanoparticlesSuperparamagneticStöber’s methodParticle sizeParticle morphologySurface amine functional groupsElectrostatic stabilityThe multisample analytical centrifuge — LUMiSizer was used to characterize the PSD of SIONPs used in this study. particle size distribution analysispsa More details Edition709 Internal reference3118 Open publication →
Lackierfähigkeit von Kunststoffrezyklaten AuthorKatharina Tonn Year2025 Source06. Mai 2025 | European Automotive & Plastic Coating LanguageGerman Pages1-34 3070LUMiFracLFracVolkswagen Group 10 more VWVolkswagen AGWolfsburgKunststoffe in großen Mengen in der Automobilindustrie eingesetzt. Allerdings spiegelt die Qualität von Kunststoffrezyklaten die individuellen und häufig unbekannten Bedingungen der vorhe- rigen Produktlebenszyklen wider. Qualitäts- schwankungen und Performanceeinbußen gegenüber der Neuware sind die Folge und erschweren einen Einsatz in anspruchsvollen Anwendungenwie lackierten Fahrzeugum- fängen. Das Risiko von Schadensbildernwie DelaminationenStippen oder Vergilbungen steigt. Vor diesem Hintergrund präsentiert der Beitrag Herausforderungen und Hebel beim Einsatz von Kunststoffrezyklaten in lackierten Anwendungen. HaftprüfungGegenüberstellung Centrifugal Adhesion Testing (CAT) (n=16) und Dampfstrahlprüfung (n=9)Konsistentere Ergebnisse mit CAT erzielbar – Unterschiede primär auf Substratseite erkennbarWechsel der Prüfmethode offenbart Einsatzpotentiale für Rezyklaten in lackierten Anwendungen More details EditionTalk LocationEUROPEAN AUTOMOTIVE & PLASTIC COATING, Frankfurt (Mörfelden), Germany, 06.-07.Mai 2025 Internal reference3070 Open publication →
Maltoheptaose-based block copolymer nanoparticles containing magnesium phthalocyanine: Formulation, photodynamic activity, release kinetic, toxicity, and biodistribution AuthorLia Mallmann Mattiazzi, Edileuza Pinto Teixeira, Brenda Bopp Baptista, Felix Alexandre Antunes Soares, Marcell Valandro Soares, Cristiane de Bona da Silva, Hong Li, Sami Halila, Marcos Antonio Villetti, Redouane Borsali Year2025 SourceJournal of Molecular Liquids LanguageEnglish Pages127737 3103LSMaltoheptaose-based block copolymers successfully encapsulate MgPcLUMiSizer analysis estimate a shelf-time of three years for the glyconanoparticles. 8 more MgPc encapsulated in glyconanoparticles generates singlet oxygen.Glyconanoparticles are biodistributed in intestinal surrounding cells of C. elegansGlyconanoparticles containing MgPc are not lethal and present low toxicity in vivo.Photodynamic therapy (PDT) has gained prominence in treating both neoplastic and non-neoplastic diseases due to the advent of new third-generation photosensitizers. This study focused on the creation of glyconanoparticles based on block copolymers (maltoheptaose-b-polystyrene and maltoheptaose-b-polymethylmethacrylate)encapsulating the photosensitizer magnesium phthalocyanine (MgPc)produced through a self-assembly process in a selected solvent mixture. The physicochemical characteristics of the polymeric micelles were analyzedmedicalmedicienpharmaceutical More details Edition433 Internal reference3103 Open publication →
Microfluidics‑on‑a‑chip for designing celecoxib‑based amorphous solid dispersions: when the process shapes the product AuthorJoana Figueiredo, Maria Mendes, Alberto Pais, João Sousa, Carla Vitorino Year2025 SourceDrug Delivery and Translational Research LanguageEnglish Pages732–752 Amorphous solid dispersions · Microfluidics-on-chip · Bioavailability · Poorly water-soluble drugs · Polymers · Performance3048LSLUMiSizer 6 more fundamental idea underlying the use of amorphous solid dispersions (ASDs) is to make the most of the solubility advantage of the amorphous form of a drugAnalytical centrifugationstability of the formulationsInspecting the stabilityA predictive assessment of the physical stability of the for- mulations F1-F9 was performed on the LUMiSizerpharmaceutical More details Edition15 Internal reference3048 Open publication →
Molecular Strategies to Overcome Sensory Challenges in Alternative Protein Foods AuthorEmrah Kirtil Year2025 SourceFood and Bioprocess Technology LanguageEnglish Pages1-33 3083LSLUMiSizernutrition 5 more Alternative proteins · Sustainability · Off-flavors · Astringency · TextureAccelerated stability analysis using analytical centrifugationoptimization · Sensory improvementEnhanced creaminess of plant-based milk via enrichment of papain hydrolyzed oleosomessoy milk More details Editionpublished online 30 May 2025 Internal reference3083 Open publication →
Monitoring of Critical Raw Material Recycling from Battery Black Mass using the LUMiReader® X-ray and LUMiSizer® AuthorMatthew A. Hood, Ute Schuldt Year2025 SourceDispersion Letters LanguageEnglish Pages5-9 3081BatteryBlack MassRecycling 8 more ValorisationLUMiReader® X-rayLUMiSizer®Lithium-ionChromatographic SeparationMethod OptimizationSlurriesThis study demonstrates the effective use of the LUMiSizer® analytical centrifuge and LUMiReader® X-Ray in separating and analysing a sediment for the presence of these critical material components More details Edition16 Internal reference3081 Open publication →
Multi-Reflectance-Spectroscopy, Part II: Optical Sensor for In-Line Monitoring of Fat and Protein in Milk-Based Products AuthorSebastian Boldt, Gert Sinn, Klaus-Henrik Mittenzwey, Ouwen Zhai, Henry Mittenzwey, Dietmar Lerche, Marco Gleiß, and Hermann Nirschl Year2025 SourceApplied Spectroscopy LanguageEnglish Pages1-14 LUMiFlectorLFlec3155This study presents an optical sensor system utilizing multi-reflectance spectroscopy (MRS) 10 more specifically designed for in-line applications to enable the real-time determination of fat and protein content in milk productssimultaneously. This method employs multiple light wavelengths and various illumination-detection geometries. A field study was conducted in a milk mixing plantwhere measurements were obtained from milk products with varying fat and protein concentrationswith a particular focus on recombined milk samples and a brief comparison to conventional milk products. In a first step the experimental data are compared with simulation data obtained from an analytical MRS formula. The fundamental spectroscopic characteristicsparticularly the dependence of reflectance values on fat concentrationsas well as the relationship between wavelength and reflectanceremained consistent. Howeversome experimental bias was observed in the absolute values when comparing the analytical and experimental results. Secondlyto get reflectance models multi-linear regressions (MLR) were carried out based on the experimental and analytical data as well fat and protein content obtained from traditional wet chemical methods. To estimate the model accuracy the root mean square error (RMSE) has been used yielding around 0.1 wt% for fat and protein. A validation procedure using recombined milk results in approximately 0.1 wt% for fat and around 0.2 wt% for protein. Finallyit is shown that the process sample temperature has only a small influence on the reflectance. In contrast the homogenization pressure significantly influences the reflectance and should be considered to ensure accurate monitoring. More details Edition79 Internal reference3155 Open publication →
Multidimensional In Situ Characterization of Surface and Free Nanobubbles in Oxidic Nanofluids AuthorAnnett Wollmann, Bernd Benker, Vinzent Olszok and Alfred P. Weber Year2025 SourcePowders LanguageEnglish Pages7 3017LFLUMiFugeLUMiSizer 2 more LS; nanopowders; bulk nanobubbles; surface nanobubbles; NTA; UV–vis extinctionsettling experiments More details Edition4 Internal reference3017 Open publication →
Nanoalum particles containing a pegylated lipid sizing agent AuthorNeal Van Hoeven, Traci Mikasa, Christopher B. FOX, Anwar Ahniyaz, Mark T. Orr, Amit Khandhar Year2025 SourcePatent application US20250241864A1 LanguageEnglish 3120Access to Advanced Health InstituteProvided herein are nanoalum particles comprising an aluminum salt and a sizing agentwherein the size of the particle ranges from about 1 nm to 450 nm. Such a nanoalum particles are stable and are amenable to a terminal sterilization step prior to vialing. Compositions comprising the nanoalum particles 8 more and the making and using of the nanoalum particles are also provided. Sedimentation Analysis Laser scattering optical profiling was conducted using the LUM GmbH LUMiReaderequipped with three lasers of wavelengths 470 nm630 nmand 870 nm. Particle settling rates were determined based on changes in the laser light transmission profile from a vertical cross-section of the sample cuvette. 4 mL of undiluted formulation were added directly to a cylindrical glass cell for analysis. Samples were measured for at 25° C. for 2-4 hours at a max tilt angle of 30° with measurement scans collected every 60 seconds. Furthermorebased on the multiwavelength analysis method (2)particle settling rates could be used to calculate volume-based particle size distributions for particles larger than ˜0.5 μm. LRPSALUMiReader PSAPSD More details Internal reference3120 Open publication →
Od dyspergowalności, poprzez stabilność, po sekrety osadów – wieloetapowa analiza oczyszczających maseczek glinkowych do twarzy AuthorA. Uhl, Ł. Giliński, J. Gilińska Year2025 SourceŚWIAT PRZEMYSŁU KOSMETYCZNEGO LanguagePolish Pages112-121 3132LUMiReader X-RayLRXLUMiSizer 14 more LScosmeticshome personal carehpcfacial maskdyspergowalnośćjednorodnośćstabilnośćprzy- spieszona separacjazawiesinyemulsjetechnologia rentgenowskaoptyczna technologia STEPoczyszczająca glinka do twarzy More details Edition4/2025 Internal reference3132 Open publication →
On the operational speed limit of magnetorheological clutches AuthorFrédérick Bérubé, Jean-Sébastian Plante and David Rancourt Year2025 SourceERMR 2025 Conference book LanguageEnglish Pages103-104 LS3082LUMiSizermagnetorheological fluid 10 more clutchsedimentationaddditivesfluid with additives at times gravityextracted sedimentation metricevolution of cip carbonyl iron particles concentration in the cakefluid withwithout additivespower transmission applicationsautomotive powertrains More details Edition19th International Conference on Electrorheological fluids and Magnetorheological Suspensions LocationConcordia University, Montreal, QC, Canada, July 7-10, 2025 Internal reference3082 Open publication →
Overall use of edible insects for producing food analogs and upcycling insect-derived ingredients from residues AuthorAli Kozlu, Nujamee Ngasakul, Iveta Klojdova, Jaroslav Havlík, Anna Mascellani Bergo, Marketa Bercíkova, Diana Karina Baigts-Allende Year2025 SourceApplied Food Research LanguageEnglish Pages100881 3068LSLUMiSizerEdible insects 12 more Lesser mealwormMilk analogsChitosan edible filmsEdible insects have been pointed out as a sustainable alternative for their use in food and feed formulations because of their content of valuable substancesincluding proteinlipidsvitaminsmineralsand functional polysaccharides such as chitin/chitosan for medical and food coating applications. This study explored the use of Alphitobius diaperinus larvae to produce milk analogs and chitosan from processed insect residues as an upcycling processing strategyInsect-based milk analogs stabilityPhase separation of O/W samples was measured by the analytical centrifuge LUMiSizer®nutrition More details Edition5 Internal reference3068 Open publication →
PALM-BASED VEGAN MAYONNAISE AuthorSAW MEI HUEY; NUR HAQIM ISMAIL; NORAZURA AILA MOHD HASSIM and SIVARUBY KANAGARATNAM Year2025 SourceMPOB INFORMATION SERIES LanguageEnglish Pages1-4 3090Head of Innovation Commercialisation CenterMalaysian Palm Oil Boardfood 11 more nutritionLFLUMiFugeLUMiSizerLSalternativeTransmission profile of the developed palm-based vegan mayonnaise sample after six months of storage at 25°CTo predict long-term stabilitythe sample was subjected to an accelerated stability test using LumiFuge at 4000 rpm for 7.5 hrsimulating the effects of 24.2 months of real-time storage More details EditionMPOB TT No. 696, 865 Internal reference3090 Open publication →
Plasma pre-treatment of pressure-sensitive adhesive AuthorV. Ginster , M. K. Heym , A. Schiebahn , and U. Reisgen Year2025 SourceTHE JOURNAL OF ADHESION LanguageEnglish Pages1-16 3136LFracLUMiFracWelding and Joining Institute 8 more RWTH Aachen UniversityPressure-sensitive adhesives (PSA) are currently being used more and more as a mounting technology and are finding their way into unique applicationse.g.for attaching exterior parts to automobiles or components in smartphonesThe pre-treatment of polymers to enhance adhesion through the application of a plasma process is a method that has been industrially validated. Howeverit should be noted that plasma pre-treatment alone is not sufficient to ensure complete cohesive failure of demanding materials without the incorporation of primers. The application of primers is a critical process involving chemicals that are hazardous to health and the environment. Given the polymeric nature of adhesivesit is pertinent to investigate whether plasma pretreatment of the adhesive can enhance the adhesion between the substrate and the adhesive. In order to evaluate the effect of the APPJ pretreatment of the PSAthe adhesive strength is tested in peel tests for the single sided tapes and in a centrifugal adhesion test (CAT) for the double sided tapes. The CAT is performed in a LUMiFrac adhesion analyzer More details EditionPublished online: 18 Dec 2025 Internal reference3136 Open publication →
Process development for the magnetic separation of lactoferrin from acid whey using bare iron oxide nanoparticles AuthorEva Maria Jennifer Krolitzki Year2025 SourceDissertation LanguageEnglish Pages1-137 3213LRPSALUMiReader PSAAcid whey (AW) is produced in large quantities as a by-product of cheese-making through acidification and contains the valuable protein bovine lactoferrin (bLF). However 13 more its physicochemical properties complicate bLF recovery via conventional downstream processesas solids in AW can block chromatographic columns. In commercial manufacturingbLF is typically isolated from skim milk using cation exchange resins in packed-bed columns. Bare iron oxide nanoparticles (BIONs)which can also function as ion exchangersare already approved as food colorants and contrast agents in medical imaging. Aiming for a cost-effective AW valorization processthis study presents a novel approach for bLF isolation using unfunctionalized BIONs in a liter-scale magnetic separation process. Sauermolke (AW) fällt in großen Mengen als Nebenprodukt der Käseherstellung durch Säuregerinnung an und enthält das wertvolle Protein Lactoferrin (bLF). Die physikalisch-chemischen Eigenschaften von AW erschweren jedoch die Isolation von bLF durch herkömmliche Aufarbeitungsverfahrenda enthaltene Feststoffe Chromatographiesäulen verstopfen können. Kommerziell wird bLF in der Regel aus Magermilch mit Hilfe von Kationenaustauscherharzen in Chromatographiesäulen isoliert. Eisenoxid-Nanopartikel (BIONs)die ebenfalls als Ionenaustauscher fungieren könnensind bereits als Lebensmittelfarbstoffe und Kontrastmittel in der medizinischen Bildgebung zugelassen. Mit dem Zielein kostengünstiges Verfahren zur Wertschöpfung aus AW zu entwickelnwird in dieser Arbeit ein neuartiger Ansatz für ein magnetisches Separationsverfahren im Litermaßstab vorgestelltbei dem BIONs ohne Oberflächenfunktionalisierung verwendet werdenum bLF aus AW zu isolieren More details LocationTUM School of Engineering and Design der Technischen Universität München, Germany Internal reference3213 Open publication →
Pulsed Laser Synthesis and Processing of Organic Drug and Nutraceutical Suspensions AuthorTina Friedenauer Year2025 SourceDissertation LanguageEnglish Pages1-187 LS3214LUMiSizerLaser synthesis and processing of colloids (LSPC) is a versatile method for producing particle suspensions to alter particle size 4 more shapeor for targeted post-treatment to control particle properties. Die laserbasierte Synthese and Prozessierung von Kolloiden (engl. laser synthesis and processing of colloidsLSPC) ist ein vielseitiges Verfahren zur Herstellung von Partikelsuspensionenum die Partikelgröße und -form zu verändern oder durch gezielte Nachbehandlung die Partikeleigenschaften zu steuern More details LocationTechnical Chemistry I University of Duisburg Essen, Germany Internal reference3214 Open publication →
