Composition, film, and display device AuthorMegumi Hayasaka, Yukako NISHIKAWA, Masayoshi TOKUDA, Mitsuo Tsuchiya Year2025 SourcePatent LanguageEnglish 3106Sumitomo Chemical Co LtdLSA composition which includes a particle and a binder component and can reduce thickening over time is provided. Provided is a composition including a particle 10 more wherein the particle includes a first particle (A-1) which is a light-emissive particlethe composition further includes at least one selected from the group consisting of a resin (B) and a polymerizable compound (C)and when the total surface area of the particles contained in 1 g of the composition is defined as Stotal and the total number of polar groups contained in 1 g of the composition is defined as PtotalPtotal/Stotal is 13.5 groups/nm2 or less. Determination of Average Particle Diameter of Second Particle (A-2) The particle size distribution of titanium oxide (TiO2) particle as the second particle (A-2) was determined on a sample for determinationa dispersion of the particle in PGMEA as a mediumusing a centrifugal sedimentary analyzer for dispersion stability/particle size distribution under the following conditionsand the volume-weighted median diameter (D50) was obtained as the average particle diameter [nm]. Analyzer: LUMiSizer 611titaniapsdpsa More details EditionUS20250207026A1 Internal reference3106 Open publication →
CONTINUOUS MANUFACTURING OF INJECTABLE NANOEMULSIONS: METHODS AND CHARACTERIZATION AuthorThomai Panagiotou and Dean Dinair Year2025 SourcePoster W0930-02-13 LanguageEnglish 3131Delphi ScientificLLCA small molecule API was encapsulated in a O/W nanoemulsion at concentrations 5-7 mg/ml. This particular API is practically insoluble in water 11 more with solubility < 0.01 mg/ml. Soybean oilegg phospholipids and API were the key ingredients in the nanoemulsionwith the oil phase being about 28 wt % of total. Nanoemulsions were manufactured using a novel Continuous emulsification method and the conventionalbatch method. Both methods rely on high pressure homogenization (HPH)which is a processing method with high energy ratesSTABILITY PARAMETERS Figure 3. Emulsion A(a) average creaming velocityand (b) separation index at 20C and 40CAnalytical centrifugation using a Lumisizer was used to measure stability parameters. LSLUMiSizerpharmaceutical More details EditionAAPS 2025 PHarmSCi 360 LocationHenry B. Gonzalez Convention Center San Antonio, TX, USA, November 9-12, 2025 Internal reference3131 Open publication →
Delivery system matrices AuthorMark J. Neveu Year2025 SourcePatent LanguageEnglish Wellomics LLC3107LSThis invention relates to delivery matrix compositions (e.g. 10 more dietary products or pharmaceuticals) and related methods. In particularthe disclosure relates to delivery matrix compositions that include temperature-dependent O/W emulsion complexeslow viscosity sheared fluid gelsand viscous hydrogels that can facilitate the delivery of a wide range of substances to the gastrointestinal tract (e.g.small intestine) of a subject. In some embodimentsthe emulsion complexes have a particle size (mean droplet diameter) of 100 to 900 nmfor example100 to 200 nmor 100 to 500 nm. Droplet size can be verified by using particle sizing instrumentssuch as the commercial Sub-Micron Particle Analyzers (LumiSizer More details EditionUS12377046B1 Internal reference3107 Open publication →
Developing Active Modified Starch-Based Films Incorporated with Ultrasound-Assisted Muña (Minthostachys mollis) Essential Oil Nanoemulsions AuthorJosé Antonio Flores-Bao, Luis Jaime Pérez-Córdoba, Patricia Martínez-Tapia, Fiorela Peña-Carrasco, Paulo José do Amaral Sobral , Izabel Freitas Moraes and Carmen Velezmoro-Sánchez Year2025 SourcePolymers LanguageEnglish Pages23 3179Minthostachys mollis; tunta starch; I-optimal design; essential oil nanoemulsions; active filmsn this studyan I-optimal design was used to select an optimal muña essential oil nanoemul- sion (MEO-NE) for application in active starch-based films. Four independent variables were used to optimize the process: emulsifier concentration (X1) (% w/w) 4 more sonication time (X2) (min)essential oil concentration (X3) (% w/w)and emulsifier type (X4) (Tween 80 or sapote gum). Accelerated Stability Test The physical stability of the MEO-NE was determined using an analytical centrifugal analyzer (LUMiSizer)Transmission profiles of MEO-NE-stabilized with the addition of Tween® 80 under optimal conditions obtained from LUMiSizer. LS More details Edition18 Internal reference3179 Open publication →
Development of Magnetic Nanoparticle-Based Processes for the Capture of Immunoglobulins AuthorInes Zimmermann Year2025 SourceDissertation LanguageEnglish Pages1-230 3186LRPSALUMiReader PSAWith the growing market demand for immunoglobulin (Ig) biopharmaceuticals 20 more the need for efficient manufacturing has become increasingly critical. Despite substantial progress in the upstream processingthe overall production efficiency remains limited by purification chal- lenges in the downstream processing (DSP). In particularthe traditional Protein A affinity chromatography capture step causes limitations that hinder progress in DSP. These include the need for extensive feed clarification to prevent column blockagelow productivity due to slow diffusive mass transportand acidic elution conditions that can damage Ig products. This thesis addresses the challenges by exploring magnetic separation as an alternative technol- ogy for the capture step.Mit wachsender Marktnachfrage von Immunglobulin (Ig) Biopharmazeutika wird die effi- ziente Herstellung dieser immer wichtiger. Trotz erheblicher Fortschritte in der Upstream- Prozessierung bleibt die übergeordnete Produktionseffizienz durch Herausforderungen bei der Aufreinigung in der Downstream-Prozessierung (DSP) eingeschränkt. Der traditionelle selek- tive Capture-Schritt basierend auf Protein A-Affinitätschromatographie hat mehrere Nach- teilewelche den Fortschritt in der DSP limitieren. Dazu zählen ein umfangreicher Bedarf an vorangehender Klärung zur Vermeidung von Säulenverstopfungeneine begrenzte Produktivität aufgrund langsamer diffusiver Massentransporte sowie potenziell produktschädigende saure Elutionsbedingungen. Diese Dissertation befasst sich mit den genannten Herausforderungenindem innovative magneti- sche Trennschritte als Alternativen für das Capture untersucht werden. Im Gegensatz zu früheren magnetischen SeparationsstudienMagnetic field in space-and time-resolved extinction profile (STEP) experimentsMagnetophoretic sedimentation velocities of particles in TBSC buffer (50 mM Tris150 mM NaCl10 mM CaCl2pH 7.5) and EDTA (100 mMpH 5.5). Magnetophoretic velocities of the particles were determined using a LUMiReader (LUM GmbHGermany) equipped with five stacked cylindrical neodymium boron ferrite (NdFeB) magnets (Webcraft GmbHGermany). The magnetic field strength over the magnets can be found in [1]. Based on space-and-time-resolved extinction profiles at 870 nm630 nmand 420 nmthe magnetophoretic velocities were determined using the software PSA-Wizard (SEPview software; LUM GmbHGermany More details LocationTUM School of Engineering and Design der Technischen Universität München, Germany Internal reference3186 Open publication →
Development of Optimized Colloidal Dispersion Containing Nanoemulsified Quercetin AuthorJéssica G. Melo, Louise M. Oliveira, Henrique L. Piva, Helinando P. Oliveira, Antonio C. Tedesco & Marigilson P. Siqueira-Moura Year2025 SourceBioNanoScience LanguageEnglish 3024LSLUMiSizerQuercetin (Qct) is a flavonoid belonging to the subclass of flavonol with recognized biological activities. However 2 more such activities are limited due to its poor aqueous solubility and low stabilityNormalized transmission profiles obtained from unloaded NE (NE1-NE5) by forced stability analysis during analytical centrifugation with LUMiSizer More details Edition15 Locationarticle number 139 Internal reference3024 Open publication →
Dielectric Elastomer Switch: Fabrication, Characterization, and Applications AuthorJianan Yi Year2025 SourceDissertation LanguageEnglish Pages1-155 3105ink Stability CharacterizationA dispersion analyzer (LUMiSizer ) with a wavelength of 470 nm was utilized to assess the sedimentation velocity (vsedin μm/s or mm/d) of CB in water. Carbon black 25 more LSextinction-weighted velocity distributionWith the growing interest in softflexibleand stretchable electronicspiezoresistive sensors are increasingly used in human motion detectionhuman-machine interactionelectronic skinhealth monitoringand soft robotics. Most conventional piezoresistive sensorshowevercan only passively measure external stimuli. Alternativelya new type of piezoresistive sensor was developed by integrating a dielectric elastomer actuator (DEA) with the piezoresistive effect on a single monolithic dielectric elastomer filmresulting in a dielectric elastomer switch (DES). This novel DES enables piezoresistivity in response to DEA actuation. HoweverDES technology has encountered challenges related to materials and manufacturing processeswhich this thesis aims to addresscarbon black (CB) inkdrop-on-demand inkjet printing was subsequently adoptedalong with the development of new inkscomprising CBchlorobenzene (CLB)and triethylene glycol monomethyl ether (TGME). The optimized ink recipe (TGME : CLB = 1:0.5) provided high stabilitysuitable particle sizegood drop formationand effective wetting on VHB. LS More details LocationTechnische Universität Dresden, Fakultät Elektrotechnik und Informationstechnik Internal reference3105 Open publication →
Dispersionsanalyse AuthorBio-Chemisches Laboratorium der Dr. Lehmann GmbH & Co KG Year2025 Sourcehttps://b-c-l.de/downloads/Dispersionsanalyse.pdf LanguageGerman Pages1-2 3072LUMiSizerLSStabilitätsanalyse von Emulsionen 1 more Partikelgrößenverteilung More details Internal reference3072 Open publication →
Effect of Bioactive Glass (BAG) on dentinal shear bond strength of composite resins using universal dental adhesive with different application modes and storage times AuthorSeyed Mostafa Mosavinasab, Kamyar Fathpoor, Babak Sarrafpoor, Sepidehsaadat Mousavinasab, Mohamad Hossein Fakour Year2025 SourceFrontiers in Dentistry LanguageEnglish Pages1-8 3076Bioactive glass 45S5; Dental Cements; Shear Strength; Dentin-Bonding Agentseffect of bioactive glass (BAG) in different forms on microshear bond strength (µSBS) of composite resin to dentin using a universal adhesive in self-etch (SE) and etch-and-rinse (E&R) modes after different storage timesThe stability of the nanoparticle suspension was verified using a separation analysis device (LUMiReader® 416.1; LUM GmbH 4 more BerlinGermany) Berlin… Stability was assessed using the LUMiReader® 416.1the use of bioactive glass nano particles (45S5) with a low percentage (1%) as a universal dental adhesive filler can increase the strength and maintain the durability of the bond to dentin. This effect is independent of the adhesive application technique More details Edition22 (24) Internal reference3076 Open publication →
Effect of Bioactive Glass on Microshear Bond Strength of Composite Resin to Dentin Using a Universal Adhesive with Different Application Modes and Storage Times AuthorSeyed Mostafa Mosavinasab, Kamyar Fathpoor, Babak Sarrafpoor, Sepidehsaadat Mosavinasab, Mohamad Hossein Fakour Year2025 SourceFrontiers in Dentistry LanguageEnglish Pages1-8 3133LUMiReader PSALRPSAThis study evaluated the effect of bioactive glass (BAG) in different forms on microshear bond strength (μSBS) of composite resin to dentin using a universal adhesive in self-etch (SE) and etch-and-rinse (E&R) modes after different storage times.Bioactive Glass 45S5; Dental Cements; Shear Strength; Dentin- Bonding Agents 4 more Preparation of BAG nanoparticles: The BAG nanoparticles (Bioglass 45S5; Nik Seram Co.IsfahanIran) were synthesized using the sol-gel methodThe stability of the nanoparticle suspension was verified using a separation analysis device (LUMiReader) More details Edition22:24 Internal reference3133 Open publication →
Encapsulation of Lactiplantibacillus plantarum subsp. plantarum in oil-phase gels O/W high internal phase emulsions: Improvement of storage stability and gastrointestinal viability AuthorEnjing Huang, Ziling Li, Fangyuan Zhou, Qinyu Chen, Jiayong He, Xiangyuan Xiong, Youfa Xie, Hongxia Gao, Liqiang Zou Year2025 SourceFood Chemistry LanguageEnglish Pages146328 3126Physical stability and microstructure Assessing HIPE stability is essential for its use as a probiotic encapsulation systemas its ability to protect active components depends on its structural integrity. The LUMifuge full-function stability analyzer records the change of HIPEs transmittance due to the change of droplet migration during centrifugationand calculates the instability index of HIPEs 4 more LFLSLUMiSizernutrition More details Edition495 Part 1 Internal reference3126 Open publication →
Enhancing the Physicochemical Properties, Bioactivity, and Functional Applications of Fresh Jujube Juice Using Media Milling AuthorHong-Yi Kang, An-I Yeh, Min-Hsiung Pan* Year2025 SourceACS Omega LanguageEnglish Pages12603–1261 LUMiCheckLC3075food 6 more nutritionBeverages Bioactive compounds Carbohydrates Fermentation NanoparticlesSuspension Stability. Stability was evaluated using a demixing tester (LUMiCheck)ffects of media milling on the physicochemical propertiesbioactive compound contentand functional applications of fresh jujube (Ziziphus jujuba Mill.) juice. More details Edition10, 12 Internal reference3075 Open publication →
Enhancing the physicochemical stability and bioaccessibility of curcumin-loaded soybean oil bodies emulsions in the in vitro elderly model AuthorWenwen Lv, Kaiyi Zou, Fengru Zhang, Yiran Jia, Ikram Alouk, Xiaoyu Li, Wei Chen, Baoguo Sun, Yanbo Wang, Duoxia Xu Year2025 SourceFood Hydrocolloids LanguageEnglish Pages110563 3027LSLUMiSizerCurcumin 14 more a hydrophobic polyphenolprovides numerous health benefitsbut its limited water solubilitystability and bioavailability hinder its applications in the food and pharmaceutical productswhile its biological fate in elderly is unclear. In this studya natural soybean oil bodies-curcumin (SOB-C) emulsion was fabricated using a pH-driven method without the use of organic solvents to minimize environmental impact. The digestive propertiescurcumin bioaccessibilityfree fatty acids (FFA)and microstructural changes of SOB-C were investigated using an in vitro elderly digestion model. The findings indicated that curcumin was successfully encapsulated within SOB with an efficiency of up to 90%. Compared to free curcuminthe curcumin encapsulated within SOB demonstrated a significant enhancement in the lightstorage stabilityand an extension of the curcumin's half-life up to 74 daysThe physical stability of SOB-C was determined by accelerating the onset of instability with a LUMiSizernutrition More details Edition158 Internal reference3027 Open publication →
ESTABILIDADE ACELERADA DE EMULSÕES POLIMÉRICAS POR FOTOCENTRIFUGAÇÃO ANALÍTICA — UMA TÉCNICA DISRUPTIVA AuthorCarlos Haroutiounian Year2025 SourceAbstract LanguagePortuguese Pages1 3127A avaliação de estabilidade de emulsões poliméricas étradicionalmentelenta e pouco resolutiva. A fotocentrifugação analítica (centrifugação com leitura óptica espaço-temporal) acelera os fenômenos gravitacionais enquanto monitora 13 more ao longo da altura da amostraa evolução dos perfis de transmissão/retroespalhamento. Esse arranjo permite quantificar cremeaçãofloculação e coalescência sem diluiçãoconvertendo sinais em métricas reprodutíveis (índice de instabilidadevelocidades de separaçãotempo de início e distribuição de velocidades). Apresentaremos como esses indicadores se correlacionam ao shelf-life em armazenamento estáticoviabilizando triagem rápida de emulsificantes/espessantescomparação objetiva entre lotes e definição de janelas de processo. Estudos de caso com látex acrílico e sistemas acrílico-estirênicos ilustram redução do ciclo de desenvolvimento de meses para horassuporte a decisões de P&D e ganho de robustez em CQ (liberação de lote com evidência quantitativa). Conclui-se que a fotocentrifugação analítica oferece um caminho robustorápido e economicamente vantajoso para projetar emulsões mais estáveis.LUMiSizerLSpolymers More details Edition18 Congresso Brasileiro de Polimeros LocationCampos de Jordao/SP, Brazil Internal reference3127 Open publication →
Evaluating ultra-fine friction grinding for the continuous production of nanofibrillated cellulose AuthorHuy Vu Duc Nguyen, Angus C.L.A. Crampton, Daniel F. Schmidt, Tim Huber Year2025 SourceCarbohydrate Polymer Technologies and Applications LanguageEnglish Pages100838 3100LSSize distribution analysis A LUMiSizer® (L.U.M. GmbHBerlin 12 more Germany) analytical centrifuge was used to characterize the equivalent hydrodynamic particle sizes and distributions of the obtained NFCpsdpsaparticle size distribution analysisvelocity distributionLumisizer analytical centrifugation technique was used to assess the impact of grinding duration on the evolution of NFC size distributionLike the Dynamic Light Scattering (DLS) techniquethe Lumisizer measures the hydrodynamic diameter by assuming that the particles are spherical. This assumption can cause inaccuracies when analyzing elongatedfibrous particles like NFC. Unlike DLShoweverthis approach enables the study of particle size and dispersion stability at realistic concentrations (i.e. without necessitating the dilution of the NFC suspensions)thus more accurately representing the state of the materials as they exit from the grinding system. Nanofibrillated cellulose (NFC) has diverse applications More details Edition10 Internal reference3100 Open publication →
Exoshield - SkRin HOA - UV Protect Velvet Haze Cream - 6662_1L.20 AuthorSO.F.I.A. Cosmetiques Year2025 Sourcein-cosmetics Global25 - Innovation Zone Guide LanguageEnglish Pages66-67 3093LUMiSIzerLScosmetics 9 more hpchome personal carePropertiesStability : 1% lumisizer (2h - 45°C)ActiveFacial careProtectionUV filtersSPF boosters More details LocationAmsterdam, NL, 8-10 April 2025 Internal reference3093 Open publication →
Fabrication of Rubus chingii Hu ellagitannins-loaded W/O and O/W emulsion gels: Structure, stability, in vitro digestion and in vivo metabolism AuthorMing-shun Chen, Xiao-yan Jia, Dong-jun Hou, Quan-yuan Xie, Dai-wei Ke, Zong-cai Tu, Lu Zhang Year2025 SourceInternational Journal of Biological Macromolecules LanguageEnglish Pages139656 3089LFLSLUMiFuge 12 more LUMiSizerurpose of this study is to construct two emulsion gel delivery systems for encapsulating ETs-enriched fractions of Rubus chingii Hu (RCHT). The effects of storageheatingpH and centrifugation on the stability of W/O and O/W emulsion gels were determined. The encapsulation efficiencyrheological propertiesin vitro releasein vitro bioaccessibilitygut microflora regulation and in vivo metabolism of emulsion gels were investigated. This study will provide suggestions and guidance for the selection of delivery systems for RCHT in actual production.Tannin is the main naturally occurring phytochemicals in Rubus chingii Hu with poor digestive stability and low bioavailability. In this studyoil-in-water (O/W) and water-in-oil (W/O) emulsion gels encapsulating Rubus chingii Hu ellagitannins (RCHT) were fabricated and their structurerheologystabilityin vitro digestion and in vivo metabolism More details Edition295 Internal reference3089 Open publication →
Gravitational Separation Monitoring by X-ray based STEP-Technology® (LUMiReader® X-Ray): Measuring Principle and Validation AuthorAnne Zierau, Martin Holke, Markus Wolff, Daniel Krause, Stephan Kirsch, Dietmar Lerche Year2025 SourceDispersion Letters LanguageEnglish Pages10-17 Separation behaviourParticle velocity distributiondispersion stabilityconsolidation 10 more X-ray attenuationvolume fractionmass concentrationsediment structureLRX3109psdpsaparticle size distribution analysisLUMiReader X-Ray 440 More details Edition16 Internal reference3109 Open publication →
Impact of Supraparticle Sizes and Morphology on Interparticle Spacing, Slurry Rheology, Coating Density, and Electrochemical Performance in Si/C Anodes for Li-Ion Batteries AuthorAdil Amin, Moritz Loewenich, Lars Grebener, Mohaned Hammad, Simon Heckenbach, Mena- Alexander Kräenbring, Ahammad Suhail Odungat, Atharva Harshawardhan Ladole, Thai Binh Nguyen, Daniel Schwabenland, Hasan Kadah Salim, Hartmut Wiggers, Doris Segets and Fatih Özcan Year2025 Sourcehttps://engrxiv.org/preprint/view/4290/7455 LanguageEnglish Pages1-36 3037supraparticlesPorous SiliconLithium ion battery 13 more Slurry processinginfluence of supraparticle sizes on the performance of Silicon/Carbon (Si/C) composite anodes for lithium-ion batteries. Supraparticleshierarchically structured agglomerates produced via spray dryingenhance the processability of Si/C nanoparticles by improving handlingpacking efficiencyand minimizing solid electrolyte interphase formationLUMiSizerLSLUMiFracLFracAdhesion strength and failure mode of coated electrodes (cohesive vs. adhesive break) were analyzed by centrifugal adhesion testinganalytical centrifugation (LUMiSizer 6514-44LUM GmbH) for assessing the supraparticle size distribution of dispersed particle More details Internal reference3037 Open publication →
Inactivation of murine norovirus using polymeric nanoparticle delivery system for oregano essential oil for food and environmental applications purpose AuthorBeatriz Pereira Savi, Catielen Paula Pavi, Bianca Costa Bernardo Port, Thiago Caon, Débora Fretes Argenta, Gislaine Fongaro Year2025 Sourcehttps://www.researchsquare.com/article/rs-6328852/v1 LanguageEnglish Pages1-15 3121Norovirusgastroenteritis outbreaksessential oil 20 more nanoencapsulationbiotechnological disinfectantpharmaceuticalmedicalNoroviruses are the leading cause of gastroenteritis outbreaks in humans worldwide. Their unique properties ensure stability over extended periods under adverse conditionswhich enhances their risk as food and water contaminants. In recent yearsintensive research has focused on the natural antimicrobial potential of plant metabolites as disinfectants against environmental pathogens. The oregano essential oil (OEO) has gained attention due to its valuable propertiesincluding antimicrobialantioxidantantiviraland antifungal activities. Howeverthe susceptibility of OEO to degradation and oxidation under environmental or storage conditionscoupled with its low water solubilityhas limited its practical applications. Nanoencapsulation has emerged as a promising strategy to overcome these limitations by prolonging shelf lifeimproving stabilityenabling controlled releaseand expanding its potential uses. In this studywe evaluated the virucidal potential of a polymeric nanoparticle incorporating Origanum vulgare essential oil against murine norovirus 1 (MNV-1)for food and environmental applications purposes.The accelerated stability study of OEO polymeric nanoparticles was performed in the LUMiSizer® equipmentLS More details Internal reference3121 Open publication →
