METALWORKING ADDITIVES - INDUSTRIAL FLUIDS & LUBRICANTS - Essentials for longer lifetime metalworking fluids AuthorKAO Corporation Year2022 Sourcehttps://www.kaochemicals-eu.com/uploads/docs/g/m/9/qny-brochure_metalworking_online.pdf LanguageEnglish Pages1-13 2954LUMiFugeLFLUMiSizer 8 more LSHLBHydropilic-Lipophilic-BalanceemulsionstabilitylubricantscoolantsKSS More details EditionEdited August 2022. EU Version Internal reference2954 Open publication →
Method of improving the texture and functionality of a dry fractionated plant protein concentrate beverage AuthorTimothy James Wooster, Marina BORTOLIN, Ludovic PENSEYRES, Pierre-Alain RICHON, Christina VAFEIADI Year2022 SourceWO2022053631A1 LanguageEnglish 2963Figure 11 : Change in Faba concentrate milk alternative (4.15% faba concentrate3.25% sucrose3.5% fat) A) viscosity or B) lumifuge instability index of C)-E) shelf stability after 25 days at 25°C as function of gellan content. 8 more LFLUMiSizerLSSociété des Produits Nestlé S.A.foodnutritionThe invention relates in general to a method of making a plant based liquidsaid method comprising dispersing triglyceride in a plant protein mixture; forming an emulsion; applying a thermal treatment to the emulsion; and applying a shear treatment to the thermal treated emulsion to form a plant based liquid. Vegetable proteins More details Internal reference2963 Open publication →
Micelas de copolímeros em bloco à base de maltoheptaose contendo ftalocianina de magnésio para aplicação em terapia fotodinâmica AuthorLia Mallmann Mattiazzi Year2022 SourceDissertação de mestrado LanguagePortuguese 2636LUMiSizerLSO desenvolvimento de novos nanocarreadores para os chamados fotossensibilizadores (FS) de terceira geração vêm contribuindo significativamente para a evolução da terapia fotodinâmica (TFD). Por apresentar máxima absorção em comprimento de onda dentro do intervalo da janela fototerapêutica (600-800 nm) 1 more baixa degradação fotoquímica e adequado rendimento quântico de oxigênio singleto (Ф More details LocationUFSM Brazil Internal reference2636 Open publication →
microparticles: Validation, measurement range, coincidence and estimation of uncertainty AuthorLerche, Dietmar; Woehlecke, Holger; Wollik, Elia; Hussels, Martin Year2022 Source9th World Congress on Particle Technology (WCPT9) LanguageEnglish Pages46 Particle size distributionparticle countsparticle concentrationuncertainty 7 more SPLS-TechnologyLUMiSpocScattering simulation3042LSpochigh resolution of number-based size distribution of nano and submicron-particles together with the level of concentration. psdpsa More details EditionABSTRACTS’ BOOK LocationMadrid, Spain, 18-22 September 2022 Internal reference3042 Open publication →
Mini-review on application of analytical centrifugation, ultracentrifugation and centrifugal devices to phase equilibria and separation processes AuthorKotaro Oshima, Kentaro Nakamura, Haixin Guo, Richard Lee Smith Jr Year2022 SourceFluid Phase Equilibria LanguageEnglish Pages113457 2677LUMiSizerLSExperimental technique 8 more NanotechnologyProcess intensificationOsmotic pressureDeep eutectic solventsSolid-liquid equilibriaAnalytical centrifugation (AC) and analytical ultracentrifugation (AUC) are now standard techniques for studying proteinsbiological molecules and polymers and are beginning to be applied to nanotechnologymaterials and chemical sciences. AC and AUC techniques allow the rapid determination of the properties of molecular species in their native solutions and provide insight into the molecular interactions of colloidal systems. More details Edition558 Internal reference2677 Open publication →
Mining Marine Metagenomes Revealed a Quorum-Quenching Lactonase with Improved Biochemical Properties That Inhibits the Food Spoilage Bacterium Pseudomonas fluorescens AuthorRami Haramati, Shlomit Dor, David Gurevich, Doron Levy, Dekel Freund, Giora Rytwo, Itai Sharon, Livnat Afriat-Jurnou Year2022 SourceApplied and Environmental Microbiology LanguageEnglish Pages1-15 2716LS; quorum-quenching lactonasequorum-sensingmetagenomics 16 more Pseudomonas fluorescensbiofilmbacterial food spoilageenzyme characterizationexoprotease activityFig. 6B shows the light transmission as measured by the LUMIsizerof P. fluorescens-treated milk-based cultures. We examined the integrated transmission percentage in the milk-based bacterial cultureswith and without purified moLRP; skim-milk medium alone was used as a control. Over timecontrol samples containing skim-milk medium alone remained as homogenous suspensions even after 10 h of centrifugationwhereas skim-milk medium inoculated with P. fluorescens started destabilizationaggregationand sedimentation processes after 4 h of centrifugation. Light transmission of bacterial cultures over time measured by LUMisizer analytical centrifuge. The graph presents the integrated light transmission of the upper 20% of each test tube with bacterial cultures against time. Bacterial cultures were incubated with and without purified moLRP. Particle velocity distribution analysis by a dispersion analyzerLUMisizer. To quantify the inhibi- tory effect of purified moLRP on milk proteolysis and sedimentation in the presence of P. fluorescenswe used the LUMisizer 6110 (LUM GmbHGermany)an analytical dispersion analyzer. More details EditionVolume 88 Issue 4 e01680-21 Internal reference2716 Open publication →
Molecular structure modification of ovalbumin through controlled glycosylation with dextran for its emulsibility improvement AuthorYimei Zheng, Yu Chang, Biying Luo, Hui Teng, Lei Chen Year2022 SourceInternational Journal of Biological Macromolecules LanguageEnglish Pages1-8 2671LUMiSizerLSOvalbumin glycoconjugates 12 more Molecular structure modificationEmulsifying propertyOvalbumin (OVA) is a high nutritious proteinbut the poor emulsibility limited its application. The present study glycosylated OVA with dextran (Dex) by controlled wetheating (60–90 °C for 3 h). Temperature was an inductive factor for glycosylation degree (DG and browning intensity)and higher temperature could accelerate the reaction. Variations in molecular structure of OVA were analyzed by SDS-PAGEFTIRfluorescence spectroscopy and UV spectroscopywhich verified successes in the generation of glycoconjugate with more flexible structure. Emulsifying activity index (EAI) and emulsion stability index (ESI) for the emulsion of OVA-Dex glycoconjugates were significantly enhanced with the increasing of glycosylation temperature. Moreoverconfocal laser scanning results revealed that the emulsion exhibited smaller size and more uniform distributionand slower transmission profiles were checked by LUMiSizer centrifugal analysis as wellconfirming the emulsibility improvement of OVA. nutritionfood More details Edition194 Internal reference2671 Open publication →
Multi-dimensional approaches for the sedimentation analysis of model systems and technical dispersions, Mehrdimensionale Ansätze für die Sedimentationsanalyse von Modellsystemen und technischen Dispersionen AuthorMaximilian Johannes Uttinger Year2022 SourceDissertation LanguageEnglish Pages1-212 2682LUMiSizerLSAnalytical centrifugation 19 more AUCFundamentals of analytical (ultra-) centrifugationAC experiments of all dispersions were carried out according to ISO 13318-2Custom-made analytical centrifuge with sector-shaped centerpieces-LUMiSIzersedimentation analysis of the particle and NP dispersionsModern particle technology is strongly focused on particle and nanoparticle systems with various applicationssuch as printable electronics or biomedical sensors. In product designthe physical properties of the particlesi.e. particle sizedensity or composition and in particular interparticle interactions define final macroscopic quantities of the particulate products. In this contextcomprehensive characterization techniques are inevitable as synthesis and process protocols require continued optimization steps. For a holistic characterization of particle dispersions directly in fluid phasea strong focus lies on fractionating techniquesin particular on a multi-dimensional sedimentation analysis. While analytical ultracentrifugation is well-established for the analysis of (biological) macromolecules and particle dispersions with high resolution and provides unique insight into interparticle interactionsanalytical centrifugation has recently emerged as a fast and efficient table-top technique for high-precision characterization of particle dispersions. While the sedimentation analysis of model systems is well-established for analytical ultracentrifugation experimentsthe full potential of analytical centrifugation must still be explored. Moreoverfor technical dispersionswhich are associated with high particle volume concentrationsconcentration-driven non-ideality phenomena can be studied using analytical ultracentrifugation or analytical centrifugation. This provides a direct link to the determination of interparticle interactions of particle and nanoparticle dispersions. In this contextanalytical centrifugation serves as a fast and efficient sample screening tool and provides access to the sedimentation properties as well as their concentration-driven effects with less experimental effort. The complex interplay between non-specific interparticle interactions and the effect of particle size and polydispersity on the sedimentation behavior needs to be fully understood to enable the development of targeted product design strategies. More details LocationTechnische Fakultät der Friedrich-Alexander-Universität Erlangen-Nürnberg , Germany Internal reference2682 Open publication →
Multi-Reflectance-Spectroscopy, Part I: Theory and Calculations Using Simulated Milk Samples AuthorHenry Mittenzwey, Klaus-Henrik Mittenzwey, Gert Sinn, Sebastian Boldt,and Dietmar Lerche Year2022 SourceApplied Spectroscopy LanguageEnglish LUMiFlectorLFlec2741Optical methods are appropriate for monitoring of constituents in suspensions and emulsions. A simple multi-wavelength 7 more multi-reflectance spectroscopic techniquecalled MRS-Technologyhe spectral behavior of the analytical reflectances is very similar to that of the numerical MC reflectances in the case of medium and low absorptions. By means of simple multilinear regression techniques (MLR)simple correlations between fat and protein volume fractions and reflectances could be generated with acceptable root mean square error (RMSE) values. Each correlation shows that best results will be achieved by using reflectances at sample-specific wavelengths for small and large measuring volumes of a sample indicating the potential of the MRS-Technology. dairymilknutritiondry matter More details Edition76, Issue 12, First published online October 5, 2022 Internal reference2741 Open publication →
Multidimensional characterization of noble metal alloy nanoparticles AuthorPaola Cardenas Lopez, Maximilian J. Uttinger, Nabi Traoré, Monica Distaso, Wolfgang Peukert, Johannes Walter Year2022 SourceInternational Conference Dispersion Analysis & Materials Testing 2022 LanguageEnglish Pages1-2 2566Multidimensional characterizationsedimentation analysisanalytical ultracentrifugation 5 more plasmonic nanoparticlesoptical back coupling methodLUMiSizerLSnew analytical method that enables multi-parameter characterization of particle size and composition distributions of noble metal alloy nanoparticles More details EditionAbstracts LocationVirtual, 24-25 January 2022 Internal reference2566 Open publication →
Multifunctional Biosurfactants with Unusual pH Sensitive Interfacial Behavior for Remediation of Iron and Zinc Sulfide Formation Damage AuthorHCA Yong, K Tooker, KV Pham, R Arriaga Year2022 Sourcehttps://onepetro.org/SPEOSS/proceedings-abstract/22OSS/1-22OSS/D011S003R002/485590 LanguageEnglish 2639LUMiSIzerLSAccelerated dispersion instability of metal sulfide particulates in surfactant solutions were assessed using a centrifugal sedimentation method on a LUMiSizer More details Internal reference2639 Open publication →
NLC a base di oli essenziali del Mediterraneo per la veicolazione di clotrimazolo: trattamento sinergico per le infezioni cutanee da Candida AuthorClaudia Carbone * Cinzia Cimino * Teresa Musumeci * Angela Bonaccorso * Rosario Pignatello Year2022 Sourcehttps://www.natural1.it/wp-content/uploads/2022/04/carbone-mag22.pdf LanguageItalian Pages56-63 2640LUMiSizerLSPer confermare la stabilità dei sistemi realizzati 5 more abbiamo sfruttato la tecnologia LUMiSizer®che offre la possibilità di ottenere maggiori informazioni sulla stabilità del campione (in termini di separazione delle particelle) rispetto ai tradizional. Il LUMiSizer® è in grado di rilevare la stabilità di una dispersione non diluita e di stimarne la shelf-life in minuti/ore anziché in mesi/annisfruttando la forza centrifuga per accelerare il verificarsi di fenomeni di instabilità (sedimentazioneflocculazione o creaming). Velocità di creaming a forza di gravità normale ottenuta dal LUMiSizer® per le NLC con lavanda e rosmarino preparate con e senza clotrimazolo. More details Editionnatural 1 maggio 2022 Internal reference2640 Open publication →
Particle Formulation Science: Principles and Practice AuthorProf Steven Abbott Year2022 Sourcehttps://www.stevenabbott.co.uk/_downloads/Particle%20Formulation%20Science%20Principles%20and%20Practice.pdf LanguageEnglish Pages1-126 LUMiSizerLS2598RST data from a LUMiSizer 4 more HSPHDPHansen SolubilityDispersibility Parameters More details Internal reference2598 Open publication →
Particle Size Control for Functionalization of Iron Oxide Nanoparticles with Potential Applications in Diagnostics AuthorHiep Vo Tran Year2022 SourceMaster’s thesis LanguageEnglish Pages1-164 LSLUMiSizer2807Sample Preparation for LumiSizer 15 more measuring the particle size of IONPs is the use of a dispersion analyzer LumiSizerIron oxide nanoparticlesIONPsinstability index of IONPsParticle size distribution of IONPs.medical pharmaceuticaldiagnosticspolyvinylpyrrolidonesilanizationcolloidal stabilitySmall average diameter along with narrow particle size distribution is required to provide a satisfactory magnetic saturation performance of iron oxide nanoparticles (IONPs) for diagnostic applications. The use of polyvinylpyrrolidone (PVP) as a coating agent has previously been reported by other studies to control the particle sizeto obtain highly monodisperse particlesand to reduce agglomerations of IONPs synthesized by the co-precipitation methodthis thesis reports the optimization of colloidal stability using various masses of IONPs and various molecular weights and concentrations of PVP for efficient coatingfollowed by silanization More details LocationNTNU Norwegian University of Science and Technology, Faculty of Natural Sciences, Department of Chemical Engineering Internal reference2807 Open publication →
Pectin Stabilized Fish Gelatin Emulsions: Physical Stability, Rheological, and Interaction Properties AuthorSheng Huang, Hui Wang, Shu Wang,Xiaomei Sha, Ning Chen, Yueming Hu, and Zongcai Tu Year2022 SourceFront Nutr. LanguageEnglish Pages961875 2696LUMiSizerLSpectin 9 more fish gelatinemulsionsnon-covalent interactionsinterface performancerheological propertiesEmulsion Stability AnalysisThe dynamic physical stability (DPS) was determined with a LUMi-Sizernutritionfood More details Edition9 Internal reference2696 Open publication →
Photo curable resin for 3D printed conductive structures AuthorShang-ChengTsai, Ling-Hsuan Chen, Chia-Pei Chu, Wei-Cheng Chao, Ying-Chih Liao Year2022 SourceAdditive Manufacturing LanguageEnglish Pages102590 2579LUMiSizerLSadditive manufacturing 15 more 3D printingConductive structuresDigital light processing (DLP)UV curable resinIn this studya new resin formulation method was developed to fabricate 3D printed conductive structures via digital light processing (DLP) 3D printing technology. Metal fillerssuch as silver-coated copper flakes (AgCu) and silver nanoparticles (AgNP)were tested for conductive resin formulation. With low UV shielding and printing derivationAgCu was selected as the conductive fillerand mixed with a photo curable acrylic resin. To resolve the sedimentation problem of metal fillerscarbon nanotubes (CNT) were added as a thickening agent to provide a supportive network to stop the metal fillers from settling. With the CNT additionAgCu up to 70 wt% can be well dispersed in the acrylic resin with both fluidity and suspension stability. The resin can be printed into 3D metal circuitry structures with a conductivity up to 1000 S/cm without sintering. 3D printingalso known as additive manufacturing technology... was measured by a centrifugal analyzer (LUMisizerLUM) at 4000 rpm. More details Edition51 Internal reference2579 Open publication →
Physicochemical and nutritional properties of high protein emulsion-type lupin-based model milk alternatives: effect of protein source and homogenization pressure AuthorMartin Vogelsang-O'Dwyer, Aylin W Sahin, Emanuele Zannini and Elke K Arendt Year2022 SourceJ Sci Food Agric LanguageEnglish Pages5086–5097 LS2984LUMiSizerLupin-based milk alternatives (LMAs) 7 more Accelerated physical stability analysis Stability was measured using an analytical centrifuge LUMiSizerSeparation rate in percentage/min for lupin-based milk alternatives and commercial products. : Plant-based milk alternatives are becoming more popular. Howevermany are low in nutrientsparticularly protein. More attention is being given to plant protein isolates / concentrates as potential ingredients in high-protein milk alternative formulations. : The effect of lupin protein source on the physicochemicalfunctionaland nutritional characteristics of model milk alternatives was investigated. Milk alternatives were produced with either blue lupin or white lupin protein isolateformulated to contain similar levels of protein and fat as low-fat cow's milk. More details Edition102 Internal reference2984 Open publication →
Platform for Active Vaccine Formulation Using a Two-Mode Enhancement Mechanism of Epitope Presentation by Pickering Emulsion AuthorGuy Mechrez, Karthik Ananth Mani, Abhijit Saha, Oded Lachman, Neta Luria, Ori Molad, Liliya Kotliarevski, Einat Zelinger, Elisheva Smith, Noga Yaakov, Dalia Shabashov Stone, Meital Reches, and Aviv Dombrovsky Year2022 SourceACS Appl. Bio Mater. LanguageEnglish Pages3859−3869 3177virus-like-particlessubunit vaccinesepitope-based vaccination 16 more Pickering emulsionplant virusLSLUMiSizermedicinemedicalpharmaceuticalThe stability of the emulsions was characterized by LUMiSizerand the results are depicted in Figure S5. The values of the instability indexThe recent emergence of the SARS-CoV-2 pandemic has emphasized the need for rapid vaccine development strategieswhich can be readily adapted to pathogen variations and to specific pathogen-related needs. The current SARS-CoV-2 vaccine technologies can be classified into two main categories: (i) nucleic-acid-based vaccineswhich include mRNAs and DNA plasmids that encode viral antigenic proteins produced by the host cellsas well as viral vector-based vaccines and attenuated live-virusesand (ii) protein-based vaccineswhich are based on the presentation of antigenic viral peptidesas well as inactivated whole virus and subunit vaccines. More details Edition5 Internal reference3177 Open publication →
Prediction of physical suspension stability in product development for shorter time-to-market AuthorDavid Hespeler Year2022 SourceInternational Conference Dispersion Analysis & Materials Testing 2022 LanguageEnglish Pages1-2 2545LUMiSizerLSsuspensions 11 more physical stabilitystability predictionsedimentationproduct developmentpharmaceuticalAbility assessment of LUMiSizer® to predict physical long-term suspension stability and identification of optimal formulation composition (type of gelling agent) for a market productsmartPearls® were incorporated in various gels for dermal applicatione.g. stabilized with the viscosity enhancer hydroxypropyl cellulose (HPC)and viscoelastic gelling agents (carrageenanpolyacrylate). To predict the long-term physical stabilityaccelerated sedimentation analysis was performed with the LUMiSizer More details EditionNominated for LUM Young Scientist Award 2022- Abstracts LocationVirtual, 24-25 January 2022 Internal reference2545 Open publication →
Preparation and characterization of ophthalmic fixed dose combination nanosuspensions AuthorKatharina Pail Year2022 SourceInaugural-Dissertation LanguageEnglish Pages136 LUMiSizerLS; 2736Sedimentation behaviour via Space and Time related Extinction ProfilingSedimentation analysis was performed via analytical centrifugation 9 more Optimization of nanosuspensions produced by wet bead milling is a complex process involving many factors that affect milling efficiency. This thesis focused on the identification of key stabilizer properties that have a direct outcome in the formation of a stable nanosuspension. Furthermorecritical process parameters in the preparation of fixed dose combination (FDC) nanosuspensions were described. Finallyformulation parameters determining the long-term physical stability of FDC nanosuspensions were described.Die Optimierung von Nanosuspensionenwelche über Nassvermahlung hergestellt werdenist komplex da viele Faktoren die Mahleffizienz bestimmen. Diese Arbeit fokussierte sich daraufCharakteristika von Stabilisatoren aufzudeckenwelche direkten Einfluss auf die Mahleffizienz haben. Des Weiteren wurden kritische Prozessparameter in der Herstellung von Kombinationsnanosuspensionen beschrieben. Abschließend wurden Formulierungsparameterwelche die physikalische Langzeitstabilität der Kombinationsnanosuspension bestimmen untersucht. Loteprednol wurde mit fünf TensidenA comprehensive stabilizer screening was initially performed on the individual drugs. Loteprednol was milled in the presence of five surfactants at two concentrations. More details LocationDepartment of Biology, Chemistry, Pharmacy of Freie Universität Berlin, Germany Internal reference2736 Open publication →
