High resolution single particle light scattering - a high-quality orthogonal method for protein aggregation studies AuthorStefan Küchler, Holger Woehlecke, Asmahan Karin Sheikhaleed, Elia Wollik, Dietmar Lerche Year2024 SourceBOOK OF ABSTRACTS LanguageEnglish Pages104 2964Protein aggregation plays an essential role in many applications. Fields of application range from medical diagnosticspharmaceuticalchemical and biotechnological applications to the food industry and beyond 6 more LUMiSpocLSpocsingle particle light scatteringSPLSsingle particle optical countercounting More details EditionAbstracts for posters LocationAUC2024 26 th International Conference on Analytical Ultracentrifugation, Banz Abbey/Germany, July 22 –27, 2024 Internal reference2964 Open publication →
Highly tunable Pickering emulsion/polymer systems: from colloids to functional surfaces AuthorGuy Mechrez Year2024 SourceInternational Conference Dispersion Analysis & Materials Testing 2024 LanguageEnglish Pages1 2948Pickering emulsions are stabilized by nanoparticles (NPs) that are self-assembled at the oil-water interface and act as physical barriers. Pickering emulsions come in the form of oil-in-water (o/w) or inverse emulsions. Inorganic NPs such as silicatitaniaand NPs from natural origin such as virus-like particles (VLPs) 2 more can act as Pickering stabilizersVLP-based Pickering-emulsion-platform is a fully synthetic approach that can be readily applied for vaccine development More details EditionAbstracts LocationBerlin, Germany, 10-11 June 2024 Internal reference2948 Open publication →
Identification of Environmentally Friendly Solvents to Exfoliate and Stabilize the Dispersions of Antimony Sulfide Nanosheets for Optoelectronic Applications AuthorPriyabrata Sahoo, Vijaya Kumar Gangaiah, Kuntal Singh, Ankita Narwal, Sandeep Kumar Reddy, Sharma S. R. K. C. Yamijala, K. D. M. RaoH and S. S. Ramakrishna Matte Year2024 SourceACS Appl. Nano Mater. LanguageEnglish Pages13447–1345 2979LSLUMiSizerAchieving dispersions of antimony sulfide (Sb2S3) in environmentally friendly solvents is of paramount importance for safer and sustainable processing due to its wide range of applications. The efficacy of liquid-phase exfoliation (LPE) depends on the choice of solvents 16 more and the determination of the Hansen solubility parameters (HSP) is crucial. In this workemploying the Hansen solubility sphere methodthe HSP values of Sb2S3 are determined to be 20.810.8and 13.4 MPa1/2which correspond to dispersivepolarand hydrogen-bonding interactionsrespectively. Environmentally friendly solventssuch as 2-butanol and isopropyl alcohol (IPA)have been identified as good solvents for exfoliation. Subsequentlythe stability of the dispersions is investigated using an analytical centrifuge. Through the in situ visualization of transmission profiles and various stability parameters like the instability indexsedimentation velocityand decay time constants2-butanol is found to have excellent dispersion stability. HSPHDP More details Edition7 Internal reference2979 Open publication →
Impact of additives on the quality of oxide/oxide tow-pregs obtained by continuous fibre impregnation AuthorZoé Borius, Antoine Débarre, Marc Singlard, Thierry Cutard, Aurélie Julian-Jankowiak Year2024 SourceComposites Part A: Applied Science and Manufacturing LanguageEnglish Pages108238 LUMiReader X-RayLRX3035Sedimentation tests were carried out by X-ray transmittance measurements of slurry over time 13 more using LumiReader X-ray deviceormulation of aqueous alumina slurries compatible with manufacturing alumina/alumina ceramic matrix composite (CMC) by a continuous tow impregnation process. Two hygroscopic organic plasticizerssorbitol and glycerolalong with a gelling powderboehmiteare evaluated for their impact on both slurry behaviour and the quality of impregnated tows. The interest of using glycerol instead of sorbitol is demonstratedas glycerol exhibits smaller impact on slurry viscosity and stabilitywhile being more hygroscopic and plasticizingenabling a reduction in organic content. Combining glycerol with boehmite powder improves the surface and the tack of impregnated towsalthough boehmite increases slurry viscosity and shear-thinning behaviour. Furthermorethermal degradations of sorbitol and glycerol are studied through thermogravimetric analysisto define an autoclave curing cycle for each plasticizer removingto achieve optimal compaction of tow-pregs and hence reduce the porosity of the resulting CMCs. More details Edition184 Internal reference3035 Open publication →
Improving the colloidal stability of pectin–phycocyanin complexes by increasing the mixing ratio AuthorStephan Buecker, Monika Gibis, Laura Bartmann, Sara Bussler, Jochen Weiss Year2024 SourceFood Science LanguageEnglish Pages1086-1097 2981arthrospira platensiscoloring foodpigment precipitation 14 more polysaccharide-protein complexspirulina blueLUMiFugeLFLUMiSizerLS; Department of Food Material ScienceInstitute of Food Science and BiotechnologyUniversity of HohenheimStuttgartGermanyGNT Europa GmbHAachenIn the food industrythe phycobiliprotein phycocyanin acts as a color pigment or the functional part of the superfood “Spirulina.” It is industrially extracted from Arthrospira platensis. More details Edition89 Internal reference2981 Open publication →
Influence of the Water Content in Polyamide 6 on Adhesion and Surface Pre-treatment for Adhesive Bonding AuthorChristoph J. A. Beier, Alexander Schiebahn, Uwe Reisgen Year2024 SourceResearch Square LanguageEnglish Pages1-13 LUMiFracLFrac2953Adhesive bonding 5 more surface pre-treatmentpolyamide 6To evaluate the effect of the surface pre-treatment mechanicallythe bond strength is tested in lap shear testsas well as in a centrifugal adhesion test (CAT) with both presented adhesives More details EditionApril 5th, 2024 Internal reference2953 Open publication →
Insights into Perovskite Nanoparticles: Surface Characterization and Dispersion Optimization through LUMiSizer Analytical Centrifuge AuthorBlaž Toplak, Leon Müller, Mohaned Hammad, Hartmut Wiggers, Doris Segets Year2024 SourceInternational Conference Dispersion Analysis & Materials Testing 2024 LanguageEnglish Pages1-2 2935LUMiSizerLSSurface Characterization 15 more Sustainable EnergyOxygen Evolution ReactionPerovskitesanalytical centrifuge (ACLUMisizer) to explore the surface characterization of spray-flame synthesized perovskite nanoparticlesfocusing on the investigation of perovskite interactions with different probe liquidsstudying interactions with bindersand addressing challenges such as delaminationoptimizing morphologyand maximizing porosity for efficient energy productionperovskite nanoparticlesLaMnO3LaFeO3and LaCoO3were examined by AC More details EditionAbstracts LocationBerlin, Germany, 10-11 June 2024 Internal reference2935 Open publication →
Insights into Reference Material Development: Certification of Submicron Particles for Size and Number Concentration AuthorMatthew A. Hood, Elia Wollik, Holger Woehlecke, Yazan Mansour, Bárbara Riera Rousset, Cornelia Hunger, Kyriakos Eslahian, Dietmar Lerche Year2024 SourceInternational Conference Dispersion Analysis & Materials Testing 2024 LanguageEnglish Pages1-2 2934Number ConcentrationReference MaterialSub-micron Particle 7 more Measurement UncertaintyLUMiSpocLSpocpolystyrene particle suspensionReference values and their corresponding expanded combined uncertainties for a concentration of 106 particles/mL were evaluated following ISO Guide 35 and ISO 17034Long-term concentration reproducibility tests made on 3 LUMiSpoc devices by 3 different users over 22 weeksA sub-micron polystyrene particles has to-date successfully been developed with a particle concentration of ca. 106 1/mL and an expanded combined uncertainty less than 15%. This is the first submicron polystyrene particle number concentration standard developed More details EditionAbstracts LocationBerlin, Germany, 10-11 June 2024 Internal reference2934 Open publication →
Instrument with an ultra-wide dynamic detection range for the optical counting and sizing of individual particles in suspensions AuthorMartin Hussels, Heinz Lichtenfeld, Holger Woehlecke, Elia Wollik, Dietmar Lerche Year2024 SourceRev. Sci. Instrum. LanguageEnglish Pages1-8 2942LUMiSpocLSpocSPLS 16 more single particle light scatteringpolystyrenegoldAupolymodal PS550 nm SIlicaEmulsionsColloidal systemsMeasuring instrumentsMetrologyNanomaterialsParticle size analysisSuspensionsLight scatteringScattering theoryFlow cytometry More details Edition95, 000000 Locationdoi: 10.1063/5.0165811 Internal reference2942 Open publication →
Interfacial Behavior and Long-Term Stability of the Emulsions Stabilized by Sugar Beet Pectin–Ca2+ Complexes with Different Cross-Linking Degrees AuthorHui Niu, Xianxiang Chen, Xianwei Chen, Haiming Chen, Zuman Dou, Wenduo Wang, Xiong Fu Year2024 SourceLangmuir LanguageEnglish Pages3935–3948 2967LUMiSizerLS; foodnutrition 8 more Recent studies showed that sugar beet pectin exhibited more excellent emulsifying properties than traditional citrus peel pectin and apple pectin ascribed to the higher content of neutral sugarproteinferulic acidand acetyl groups. It is precisely because of the extremely complex molecular structure of pectin that the emulsifying properties of the pectin–Ca2+ complex are still unclear. In this studySBP-Ca2+ complexes with different cross-linking degrees were prepared. Subsequentlytheir interfacial adsorption kineticsthe resistance of interfacial films to external perturbancesand the long-term stability of the emulsions formed by these SBP-Ca2+ complexes were measured. Carbohydrates Emulsions Gels Interfaces Liquids More details Edition40/7 Internal reference2967 Open publication →
Interfacial Properties Dominate over Bulk Solvent Properties in Liquid Phase Exfoliation: an Experimental Study using Dispersion Analyser AuthorPriyabrata Sahoo, H. S. S. Ramakrishna Matte Year2024 SourceInternational Conference Dispersion Analysis & Materials Testing 2024 LanguageEnglish Pages1-2 2923LUMiSizerLSLiquid phase exfoliation 10 more 2D materialsdispersion stabilityHansen solubility parameterHSPLiquid phase exfoliation (LPE) is one of the most successful techniques to obtain two-dimensional (2D) materials like grapheneboron nitrideMXeneetc.to utilize their exotic properties in various applicationsA dispersion analyser (LUMiSizer) is employed to understand the exfoliation efficiency and stability of the dispersions obtained in various solvents. More details EditionNominated for LUM Young Scientist Award 2024- Abstracts LocationBerlin, Germany, 10-11 June 2024 Internal reference2923 Open publication →
ISO 9276-1:1998/Cor 1:2004 Representation of results of particle size analysis — Part 1: Graphical representationTechnical Corrigendum 1 AuthorISO TC 24 Particle characterization including sieving SC 4 Year2024 Sourcewww.iso.org LanguageEnglish Pages1- LUMiSizerLSLUMiReader PSALRPSA 5 more LSpocLUMiSPocLUMiReader X-RayLRX3087 More details Internal reference3087 Open publication →
Liposomal Advanced Delivery AuthorQuest Nutra Pharma - QUEST VITAMINS LIMITED Year2024 SourceHome Technical Papers Liposomal Advanced Delivery LanguageEnglish 3009quest nutra pharmapharmaceuticalParticle size plays a vital role in nanoparticle adhesion to and interaction with biological cells in the body.1 2 At Quest we use Liposomal nutrients within a particle size of 200-400 nanometres (nm) 4 more ensuring they are a highly effective delivery system. The size of the liposomes and their particle size distribution are determined using a LUMiSizer® 651 particle size analyzer. psdpsaparticle size distribution analysisQuest Nutra Pharma - QUEST VITAMINS LIMITED More details Editionfound online on 14.1.2025 Internal reference3009 Open publication →
LUMiSizer as the universal tool for accessing the kinetic stability of nano ZrO2-based ceramic suspension for DLP printing – correlative study with the corresponding rheological properties AuthorPatrik Sokola Year2024 SourceInternational Conference Dispersion Analysis & Materials Testing 2024 LanguageEnglish Pages1-2 2951dispersiondynamic viscosityDisperbyk 6 more depletion flocculationsedimentation LUMiSizerLSDigital Light Processing (DLP)stability of zirconia ceramic suspensionsSedimentation profiles More details EditionAbstracts LocationBerlin, Germany, 10-11 June 2024 Internal reference2951 Open publication →
Materials testing using centrifuge technology - a journey through time from 2004 to 2024 AuthorU. Beck, U. Rietz, S. Hielscher-Hofinger, J. M. Stockmann Year2024 SourceInternational Conference Dispersion Analysis & Materials Testing 2024 LanguageEnglish Pages1-2 2960LUMiFracLFracBAM 6 more PTJcentrifuge technology (CAT-Technology: Centrifugal Adhesion Testing Technology)materials testingmultiple-sample testingtensile and compressive stress conditionsadhesive and bonding strength More details EditionAbstracts LocationBerlin, Germany, 10-11 June 2024 Internal reference2960 Open publication →
Membrane-free Removal of Hydroxide Precipitates by Continuous Ultrasonic Filtration AuthorJames E. Coons, Audrey R. Roman, Keri R. Campbell, and Karla A. Erickson Year2024 SourceInternational Conference Dispersion Analysis & Materials Testing 2024 LanguageEnglish Pages1-2 2926HydroxideDewateringSettling Velocity 12 more Ultrasonic FiltrationHydroxide precipitation is used to reduce dissolved metals in industrial wastewatersbut dewatering the solids with membrane filters or other conventional technologies poses challenges. In the nuclear industrychemical treatment of wastewater is performed in constrained glovebox spaces and maintaining processing rates is essential for expeditious waste removal. Water-swelled precipitates and fouled membranes lead to choked filtration rates commensurate with evaporation [1]. Ultrasonic filtration is an under-utilizedlow-maintenance technology that uses a silent standing wave to trap and concentrate particleswhile continuously clarifying a portion of the suspension and thus avoiding membrane filters altogetherAn analytical photo centrifuge (LUMiSizerLUM GmbHBerlin) was applied to the precipitates to measure their settling characteristics (i.e.settling velocity and cake volume) prior to ultrasonic filtrationand settling velocity was found to be the only material-independent predictor of dewatering performanceLS More details EditionAbstracts LocationBerlin, Germany, 10-11 June 2024 Internal reference2926 Open publication →
Meta-Analysis and Analytical Methods in Cosmetics Formulation: A Review AuthorFelipe Rico, Angela Mazabel, Greciel Egurrola, Juanita Pulido, Nelson Barrios , Ronald Marquez and Johnbrynner García Year2024 SourceCosmetics LanguageEnglish Pages1 2972LUMiSizerLShome and personal care 23 more hpcBelcorpResearchDevelopment & InnovationTocancipaColombiaDepartment of Forest BiomaterialsNorth Carolina State UniversityRaleighcosmetics; formulation; chromatography; olfactometry; stability; rheology; surface tension; colorimetry; microstructure; biobased materialsAnalytical centrifugation (AC) is a reproducible and versatile techniqueinitially used in the evaluation of macromolecules in a solution [134135]. Howeverwith the development of new technologies and softwareits applications have expanded considerablyparticularly in dispersed systems. This technique facilitates the characterization of particle or droplet size distributiondensitydiffusion coefficientssedimentation velocityand equilibrium sedimentation of the dispersed phase in cosmetic matrices such as emulsions and suspensionsCurrentlythere are many AC equipment options available (Table 5). Howeverthe LUMiSizer is the most commonly used for evaluating the stability of cosmetic matrices due to its moderate cost and working range with respect to particle size More details Edition11 Open publication →
Methods for treatment of pain with cannabinoids AuthorMark. J. ROSENFELD, Sohail R. ZAIDI Christopher B.G. MOORE Year2024 SourceUS20240316075A1 LanguageEnglish 3218Lyotropic Delivery Systems LtdANANDA Scientific IncDisclosed herein are methods of effectively treating or preventing Pain 6 more chronic non-cancer pain (CNCP)chronic reticular painand opioid sparing in subjects utilizing chronic opioid therapy (COT) with pharmaceutical compositionsas well as kits containing the compositions and instructions for carrying out the method.The examination of the physical stability of the Composition A was conducted using the LUMiFuge™ analytical centrifugation for rapid and efficient measurementenabling prediction of physical stability and shelf life of a product. The liquid nanodomains of the formulation were shown to be stable a 3K rpm for over 17 hoursconditions equivalent to 2 years of storage. More details EditionPatent application Internal reference3218 Open publication →
Mikro- und Nanopartikel überall – auch in unserem Trinkwasser? AuthorMatthew A. Hood, Susan Strohschein-Lerche, Dietmar Lerche Year2024 SourceF & S Filtrieren und Separieren LanguageGerman Pages1-3 2955Einzelpartikelstreuphotometer LUMiSpocLSpocFür die Bestimmung von wichtigen Merkmalen wie Partikelanzahl 5 more -größe und -konzentration sowie deren Verteilungen wurde ein Einzelpartikel-Streulichtphotometerbasierend auf der SPLS-Technologie (Single-Particle-Light-Scattering) entwickelt. Aufgrund des großen dynamischen Messbereiches ist es erstmals möglichNano- und Mikropartikel in Suspensionen und Emulsionen im Bereich von 40 nm bis 8 μm zu vermessenIn diesem Artikel werden exemplarisch Ergebnisse zur Anzahlbestimmung und Konzentration partikulärer Verunreinigungen von verschiedenen Reinst-Mineral- und Trinkwässern sowie im Labor hergestellten bzw. kommerziellen Lösungen vorgestellt More details Edition03 | 2024 Internal reference2955
Millifluidic magnetophoresis-based chip for age- specific fractionation: evaluating the impact of age on metabolomics and gene expression in yeast AuthorL. Wittmann, M. Eigenfeld, K. Büchner, J. Meiler, H. Habisch, T. Madl, R. Kerpes, T. Becker, S. Berensmeier and S. P. Schwaminger Year2024 SourceLab Chip LanguageEnglish Pages2987-2998 2970LRPSA; LUMiReader PSASaccharomyces yeast is a valuable model organism for aging researchoffering insights into two distinct aging processes: chronological aging 9 more which is defined by the survival time of the celland replicative agingcharacterized by the number of division events a cell undergoes before reaching senescence. Senescencea key aging markerimpedes cellular repair and is linked to age-related diseases.1 The process of asymmetric cell division in yeastwherein mother cells generate a finite number of daughter cellspresents a unique opportunity to gain a deeper understanding of these aging dynamics.A novel millifluidic process introduces age-based fractionation of S. pastorianus var. carlsbergensis yeast culture through magnetophoresis. Saccharomyces yeast is a model organism for aging research used in various industries. Traditional age-based cell separation methods were labor-intensivebut techniques like magnetic labeling have eased the process by being non-invasive and scalable. Our approach introduces an age-specific fractionation using a 3D-printed millfluidic chip in a two-step processensuring efficient cell deflection in the magnetic field and counteracting magnetic induced convection. The magnetophoretic sedimentation velocity was measured by the LUMiReader 4532–123 More details Edition24 Internal reference2970 Open publication →
